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faculty mentors

research description

Cell Biology/Bone. Research focus is on the molecular genetics of the repair and regeneration of skeletal tissues and skeletal development.

representative publications

Lu H, Kraut D, Gerstenfeld LC, Graves DT. Diabetes interferes with the bone formation by affecting the expression of transcription factors that regulate osteoblast differentiation. Endocrinology. 2003 Jan;144(1):346-52

Cullinane DM, Fredrick A, Eisenberg SR, Pacicca D, Elman MV, Lee C, Salisbury K, Gerstenfeld LC, Einhorn TA. Induction of a neoarthrosis by precisely controlled motion in an experimental mid-femoral defect. J Orthop Res. 2002 May;20(3):579-86.

Javed, A., Barnes, G. L., Jasanya, B. O., Stein, J. L., Gerstenfeld, L., Lian, J. B. and Stein, G. S. <ONLINE> (2001) Runt homology domain transcription factors (Runx, Cbfa, and AML) mediate repression of the bone sialoprotein promoter: evidence for promoter context-dependent activity of Cbfa proteins. Mol. Biol. Cell. (8):2891-905.

Harper, J., Gerstenfeld, L. C., and Klagsbrun, M <ONLINE>. (2001) Neuropilin-1 expression in osteogenic cells: down-regulation during differentiation of osteoblasts into osteocytes.
J. Cell Biochem. 81(1):82-92.

Wang, J., Yang, R., Gerstenfeld, L. C. and Glimcher, M. J. (2000) Characterization of demineralized bone matrix-induced osteogenesis in rat calvarial bone defects: III. Gene and protein expression. Calcif. Tissue Int. 67(4):314-20.

Kuhn, L. T., Wu, Y., Rey, C., Gerstenfeld, L. C., Grynpas, M. D., Ackerman, J. L., Kim, H. M. and Glimcher, M. J. (2000) Structure, composition, and maturation of newly deposited calcium-phosphate crystals in chicken osteoblast cell cultures. J. Bone Miner. Res. 15(7):1301-9.